Function agnoprotein

• Maturation/Nuclear egress :

• VP1 localization perinuclear
• Dissociation LBR1 - HF1®
• Dissociation FEN microtubules - FEZ1

• Transcription :

• Increased P21 expression – p53
• Reduced transcription viral promoters – LT-Ag & YB1

• DNA repair :

• Ku70 and Ku80