History

• • • First human virus identified (1901) => complicated life cycle.
    • Widespread in tropical countries since 15th century : devastating epidemics with high mortality => no infectious agent isolated from infected patients ?!
    • Blood sucking insect plays a role ! Dr. Jesse Lazear (Cuba) gave his life to demonstrate mosquito transmission
    • • Vector = Aedes aegypti or Haemagogus spp. mosquito
      • Name from ensuiing jaundice