Accessory proteins

• • 2ABC :
  • • • 2A : protease
      • 2B : membrane permeabilization and inhibition of the exocytic pathway
      • 2C: NTPase, helicase; anchors RNA polymerase to cellular membranes, membrane proliferation
  • 3ABCD
  • • • 3AB : membrane bound Vpg donor, cofactor for 3Dpol [poly(rC) -binding protein]
      • 3B (VPg): primer for RNA synthesis [poly(A)-bi prot]
      • 3CDpro : viral protease that cleaves 3CD and 3AB
      • 3Dpol : RNAdep. RNApol for replication .. .. ..