characteristics

• 65-70nm, 240 monomers, T4

• 5' cap (viral enzymes), poly A (encoded)

• Replication cycle :

• • • Glycoproteins for attachment
    • Two replication rounds :
    • • • 1) 4NS @ 5'end translated as polyprotein, then self cleavage -> gene expression and replication
        • 2) Structural proteins, negative sense fragment
    • Assembly @ cell surface, budding (envelope)