Vaccine

• veternary vaccine or mosquito control

• Very recently : new vaccine for humans !

• • recombinant WN/DEN4¢30
  • • • membrane precursor and envelope glycoprotein of dengue 4 replaced by corresponding WN genes (NY99)
  • greatly reduced neurovirulence and -invasiveness, complete protection, reduced replication, compatible with dengue virus vaccine, inhibited from returning to natural transmission cycle