PKC pathway

• RTK – PLC° - PKC

• GPCR - PLC¯ - PKC

• TF as substrates:

  • vitamineD receptor, RAR
  • MAPK (Raf kinase) and thus TF that are substrates of MAPK pathways
  • CREB in vitro, in vivo PKC stimulates AC => PKA pathway
  • NfkB, SP1, STAT, p300, HSF, SMAD, pX