A cell morphology study

• Results :

• • • identified +/- 100 genes visible loss of function
    • gene function = determined by network of functional interactions of many proteins
    • • expression levels ≠ functional consequence of KD
    • co-screen PTEN RNAi => new modifiers
    • • Akt, PI3K92E, slipper, wee, DAG kinase, MK2