Product Synonyms Structures Inhibits kinase Clinical

































Back

















































































































































































































































































































































































































































































ABX-EGF Panitumumab MAb EGFR II























































































































































































































































AG-013736


VEGF, PDGFR
II























































































































































































































































AMN-107 		NVP-AMN107 Bcr-Abl II























































































































































































































































Angiozyme RPI4610 Ribozyme VEGFR1 II























































































































































































































































AP23573

mTOR II























































































































































































































































ARRY-142886 AZD6244 MEK1/2 I























































































































































































































































Avastin Bevacizumab MAb VEGFR I-II-III























































































































































































































































AZD2171

VEGFR1,2,3 I























































































































































































































































BMS-354825
Bcr-Abl and Src inhib I























































































































































































































































Bryostatin 1
PKC I-II























































































































































































































































CCI-779 Cell Cycle Inhibitor, Temsirolimus mTOR II-III























































































































































































































































CEP701 KT-5555 FLT3, FMS, PDGFR II-III























































































































































































































































CEP751 KT-6587 (prodrug=CEP2563) RETkinase, FLT3 I-II























































































































































































































































CEP5214 CEP7055= prodrug (see side group)
VEGFR I























































































































































































































































CGP41251 PKC412
PKC II























































































































































































































































CI-1040 PD0325901 MEK1 II























































































































































































































































CP547632

VEGFR2, fGFR II























































































































































































































































CI-1033 PD183805, Canertinib dihydrochloride EGFR I-II-III























































































































































































































































EKB-569 EGFR kinase inhibitor 86 I























































































































































































































































EMD-72000 Matuzumab MAb EGFR II























































































































































































































































Enzastaurin LY317615.HCl
PKCbeta I-II























































































































































































































































Erlotinib TARCEVATM, NSC718781, CP-358774, OSI-774, R-1415 EGFR III























































































































































































































































Gefitinib Iressa, ZD1839 EGFR II-III























































































































































































































































Genistein

non-specific TK inhibitor I























































































































































































































































HKI-272 Compound 25O
ErbB2/4 I























































































































































































































































Imatinib ST-1571; Gleevec;CGP-57148B BCR-Abl IV























































































































































































































































IMC-C225 Erbitux, Cetuximab MAb EGFR III























































































































































































































































ISIS-3521 LY900003, Affinitak, Aprinocarsen, CGP64128A, ISI641A as PKC II























































































































































































































































ISIS-5132 CGP69846A as Raf1 II























































































































































































































































KRN-951

VEGFR I























































































































































































































































Lapatinib GW2016, GW-572016, 572016, Lapatinib ditosylate ErbB1 and 2 II























































































































































































































































LErafAON
as c-RAF I























































































































































































































































MDX-447
MAb EGFR II























































































































































































































































MLN-518 CT53518 KIT, PDGFR, FLT3 I-II























































































































































































































































ON-012380
BCR-ABL III























































































































































































































































Perifosine KRX0401, NSC639966, D-21266 PI3K-Akt/PKB II























































































































































































































































Pertuzumab Omnitarg, rhu-Mab2C4 MAb ErbB2 II























































































































































































































































PKI166 CGP-75166
ErbBr2, Met, Kit,TLK I-II























































































































































































































































RAD001 Everolimus
mTOR II-III























































































































































































































































Semaxanib SU5416
VEGFR1/2, bFGF, PDGFR I – stop























































































































































































































































SKI-606

Src I























































































































































































































































Sorafenib Bay 43-9006 Raf, PDGFR, VEGFR III























































































































































































































































SU6668
PDGFR, VEGFR2, FGFR I – stop























































































































































































































































Sutent SU11248, sunitib malate VEGFR, PDGFRalpha, cKit, FLT3 II-III























































































































































































































































TAK165 Mubritinib
HER2 I























































































































































































































































TheraCim h-R3 Nimotuzumab MAb EGFR II























































































































































































































































Trastuzumab Herceptin MAb ErbB2 I-II-III























































































































































































































































UCN-01

PKC II























































































































































































































































Vatalanib PTK787, ZK222584 VEGFR 1,2 II-III























































































































































































































































ZD-6474 ZactimaTM VEGFR2, Ret, EGFR II-III